منابع مشابه
Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y
Nucleosomal incorporation of specialized histone variants is an important mechanism to generate different functional chromatin states. Here, we describe the identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y. Their messenger RNAs are found in certain human cell lines, in addition to several normal and malignant human tissues. In keeping with the...
متن کاملH3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis
Dynamic changes in histone modifications under various physiological cues play important roles in gene transcription and cancer. Identification of new histone marks critical for cancer development is of particular importance. Here we show that, in a glucose-dependent manner, E3 ubiquitin ligase NEDD4 ubiquitinates histone H3 on lysine 23/36/37 residues, which specifically recruits histone acety...
متن کاملTo be or not to be: the early history of H3 and H3+.
Triatomic hydrogen became a major research area only after 1980, but its history goes back to J. J. Thomson's discovery in 1911. In fact, the possible existence of H(3) was suggested as early as 1895. This paper outlines the history of H(3) and H(3)(+) up to the mid-1930s, when chemists and physicists ceased to believe in the existence of the H(3) molecule. In the intervening years, there was a...
متن کاملDifferences in Specificity and Selectivity Between CBP and p300 Acetylation of Histone H3 and H3/H4
Although p300 and CBP lysine acetyltransferases are often treated interchangeably, the inability of one enzyme to compensate for the loss of the other suggests unique roles for each. As these deficiencies coincide with aberrant levels of histone acetylation, we hypothesized that the key difference between p300 and CBP activity is differences in their specificity/selectivity for lysines within t...
متن کاملThe Homology and Cohomology Groups of H3
A free resolution of Z for the integral group ring of the three-dimensional Heisenberg group has been constructed by extending Lyndon’s partial resolution. The integral homology and cohomology have been calculated from there. 3 H AMS Classification: 18G, 20J.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Astronomy & Geophysics
سال: 2010
ISSN: 1366-8781
DOI: 10.1111/j.1468-4004.2010.51625.x